Best Pest Control Services in Charleston, SC
24 companies listed · 18 in Charleston · 2 open 24/7 · 6 open weekends · all 24 rated 4.5+
Data verified October 18, 2026
Mosquitonix
Kopex Pest Control
Ledford's Termite & Pest Control
Reif Environmental
Cingo
Listed for homeowners in and around Charleston, SC, these 24 companies treat pest problems in homes. The pests each company names, its licensing claims and its hours come from its own site; ratings and the quoted comments come from public reviews.

Area overview: Charleston, SC
18 of the 24 companies we list are based in Charleston; the other 6 serve Charleston from North Charleston (9 mi) and Summerville (18 mi). The companies on this page are rated from 4.5 to 5.0 across 2,724 reviews; 12 have 50 or more reviews. When customers rate these companies on specific qualities, they most often praise professionalism (95%), responsiveness (76%) and quality (73%). The topics that come up most in reviews of the companies on this page are "communication", "informative" and "knowledge". 2 are open around the clock; 6 are open on Saturdays and 2 on Sundays. The services the companies on this page list most often on their websites are mold remediation (2), pest control (2) and termite control (2). 4 show a license on their websites and 4 have a BBB rating of A or A+. Domain records put 13 websites of the companies on this page at ten or more years old; the oldest dates from 1999. 2 offer emergency call-outs; 1 offers financing or payment plans; 10 give free estimates; 9 are family- or locally-owned and 1 lists coupons or special offers. We count these figures across the companies on this page; distances are straight-line, and hours and prices change, so confirm the details with the company before you book.
Which pest control companies listed for Charleston come out at night?
Around-the-clock availability is stated by 2 of the 24 listings here. A wasp nest by a doorway or a rat in a bedroom is worth an after-hours call. Most other infestations are better handled in daylight, when a technician can actually inspect the crawl space.