Best Commercial & Office Cleaning in San Antonio, TX
23 companies listed · all 23 in San Antonio · 3 open 24/7 · 15 open weekends · 22 rated 4.5+
Data verified October 28, 2026
Angel Maids
Lupe's Home & Office Cleaning
Maids on a Mission
OCD Cleaners
Upright Cleaning
Listed for businesses in and around San Antonio, TX, these 23 companies hold commercial cleaning contracts. Contract cleaning is priced off a written scope and a frequency schedule, so two quotes are only comparable when both are working from the same specification.

Area overview: San Antonio, TX
All 23 companies we list here are in San Antonio itself. We have 66 companies in San Antonio on file; this page shows the highest-rated 23. The companies on this page are rated from 4.0 to 5.0 across 4,324 reviews; 9 have 50 or more reviews and 22 are rated 4.5 or higher. When customers rate these companies on specific qualities, they most often praise professionalism (90%), quality (89%) and responsiveness (78%). The topics that come up most in reviews of the companies on this page are "price", "communication" and "estimates". 3 are open around the clock; 15 are open on Saturdays and 7 on Sundays. The services the companies on this page list most often on their websites are office cleaning (4), residential cleaning (4), deep cleaning (3), window cleaning (3) and carpet cleaning (2). 5 have a BBB rating of A or A+. 14 have ten or more years of experience, the longest 70 years. 3 offer emergency call-outs; 8 give free estimates; 4 are family- or locally-owned and 2 list coupons or special offers. We count these figures across the companies on this page; hours and prices change, so confirm the details with the company before you book.
Do any of these companies clean around the clock?
Around-the-clock availability is stated by 3 of the 23 commercial cleaning companies here. In this trade that usually means an emergency call out for a flood, a burst pipe or a biohazard rather than a crew standing by, so ask what the out-of-hours number actually reaches.