ASF Clean Team
“The guys were super friendly and left the area surrounding my house cleaner than before they arrived after removing a huge pile of pine needles from my gutters and roof.”
Best Commercial & Office Cleaning near South San Francisco, CA
3 of these companies are based in South San Francisco; the others serve South San Francisco from San Francisco (7 mi).
4 open 24/7 · 10 open weekends · all 14 rated 4.5+ · 3 show a license
Data verified October 18, 2026
Berryclean
“Did a fantastic job on cleaning the garages and my in-law unit.”
Biohazard Pro-Tec Crime Scene Cleanup
“They came in a timely manner, very professional and nice people, definitely recommend.”
Lava Steemer
“Overall, a pleasure to work, with with fair rates and high quality services.”
Greenterra Cleaning Service
“We had Yessenia came to our house this week and she was amazing, leaving our home clean and beautiful.”
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Vine House Cleaning
“I love Vine cleaning services, they not only did accommodate my tight schedule, but they also did a fantastic job.”
Listed for businesses in and around South San Francisco, CA, these 14 companies hold commercial cleaning contracts. Contract cleaning is priced off a written scope and a frequency schedule, so two quotes are only comparable when both are working from the same specification.
Area overview: South San Francisco, CA
The 14 companies on this page are rated from 4.8 to 5.0 across 1,412 reviews; 8 have 50 or more reviews. When customers rate these companies on specific qualities, they most often praise professionalism (88%), quality (87%) and responsiveness (76%). The topics that come up most in reviews of the companies on this page are "communication", "price" and "estimates". 4 are open around the clock; 10 are open on Saturdays and 4 on Sundays. The services the companies on this page list most often on their websites are commercial cleaning (2), house cleaning (2) and office cleaning (2). 3 show a license on their websites and 4 have a BBB rating of A or A+. Domain records put 3 websites of the companies on this page at ten or more years old; the oldest dates from 1996. 4 offer emergency call-outs; 9 give free estimates; 2 are family- or locally-owned and 1 lists coupons or special offers. We have a website on file for all 14 of the companies on this page; 10 publish a contact page; 12 list a public email and 6 take bookings online. We count these figures across the companies on this page; distances are straight-line, and hours and prices change, so confirm the details with the company before you book.
Does a contractor need an address in South San Francisco?
An address in South San Francisco is given by 3 of the 14 commercial cleaning companies here; the others come from other towns within 20 mi. For nightly work, the supervisor's drive matters more than the office address, since a site that is an hour from the nearest manager gets inspected less often.
Cleanerific Commercial Cleaning & House Cleaning
“I appreciate how friendly, professional, and responsive the team is.”
Celestial Cleaning Service
“Also, they were going to be delayed due to traffic but kept me up to date on their eta.”
MCS Cleaning Services Inc.
“They are always willing to go the extra mile to honor my requests, always on time, super friendly and communicative, and I am always grateful to come home to a pristine apartment!”
Bela Cleaners
“We have been using Lily and her team for about 6 months and love them!”
Miros Cleaning
“I also appreciate that they keep the people consistent which puts my mind at ease because they're already familiar with me and what I like them to focus on.”
Rosalein Cleaning
“We've used Rosa Lein for over two years, and have always been satisfied!”
Cappstone Inc.
“Michael was quick to respond and explain everything I needed to do that I would need to welcome back employees to our building.”
Maintenance Systems Management
“Would recommend using them to any business that doesn't have an internal maintenance dept.”
Why these companies made our list
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