Best Drain Cleaning Services near South San Francisco, CA
2 of these contractors are based in South San Francisco; the others serve South San Francisco from towns including San Francisco (7 mi), San Mateo (9 mi) and San Carlos (14 mi).
8 open 24/7 · 12 open weekends · 13 rated 4.5+ · 9 show a license
Data verified October 18, 2026
Genteel Plumbers
O'Grady Plumbing
Heise's Plumbing
Lutz Plumbing Inc
Advanced Plumbing & Drain
The 14 companies listed for South San Francisco, CA clear blocked drains and sewer lines. Hours, jetting and camera work, and free estimate claims come from each company's own website. Ask who carries their own jetter rather than subcontracting it before you book.

Area overview: South San Francisco, CA
The 14 contractors on this page are rated from 4.3 to 5.0 across 5,027 reviews; all 14 have 50 or more reviews and 13 are rated 4.5 or higher. When customers rate these contractors on specific qualities, they most often praise professionalism (93%), responsiveness (81%) and quality (73%). The topics that come up most in reviews of the contractors on this page are "efficient", "estimates" and "price". 8 are open around the clock; 11 are open on Saturdays and 11 on Sundays. 9 show a license on their websites and 6 have a BBB rating of A or A+. 11 have ten or more years of experience, the longest 93 years. 8 offer emergency call-outs; 2 offer financing or payment plans; 7 give free estimates; 8 are family- or locally-owned and 7 list coupons or special offers. We have a website on file for all 14 of the contractors on this page; 13 publish a contact page; 11 list a public email and 3 take bookings online. We count these figures across the contractors on this page; distances are straight-line, and hours and prices change, so confirm the details with the contractor before you book.
Are any of the listed drain crews available overnight?
Overnight availability is claimed by 8 of the 14 listings here. A backup that has reached the floor is worth the night rate, because standing sewage is a health problem, not a plumbing one. A slow sink is not. Ask what the after-hours charge covers and whether camera work waits for daylight.