Best Pest Control Services near La Mesa, CA

1 of these companies is based in La Mesa; the others serve La Mesa from towns including Santee (6 mi), San Diego (7 mi) and Lemon Grove (2 mi).

1 open 24/7 · 6 open weekends · all 15 rated 4.5+ · 5 show a license

Data verified October 18, 2026

Knotts Pest Control

Knotts Pest Control

4.6 7 reviews
“Took care of mud dauber nest as well as whole property assessment.”
Free estimatesLicensedSince 1981Serves San Diego CountyBBB A+
5141 Guild St
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Xtermite Inc

Xtermite Inc

4.6 48 reviews
“Inspector and exterminators were very professional when they came out to my home.”
California license #3336Insured2-yr warrantySince 1998Serves San Diego County, Orange County, Riverside CountyBBB A+
Santee, CA · 6 mi from La Mesa
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Harbor Pest Control

Harbor Pest Control

4.7 46 reviews
“He is so knowledgeable, caters to our needs and he even fixed the holes in the screens around the base of the house so critters cannot get in!”
Since 1948Serves Coronado, La Jolla +2Free consultationBBB accreditedFamily-ownedLocally owned
San Diego, CA · 7 mi from La Mesa
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Nixtermite Inc.

Nixtermite Inc.

4.8 41 reviews
“As an agent, I'm always looking to find the best service for my clients and I trust NIX to get the job done!”
Coupons & offersSince 1998Serves San Diego CountyFamily-ownedBBB A+Financing
Bonita, CA · 7 mi from La Mesa
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Thrasher Pest Control

Thrasher Pest Control

4.9 50 reviews
“Nick was not only full of the information I needed, but available, almost instantly, by text.”
Same-day response6,500+ clients servedServes San Diego CountyFamily-ownedLicensedSince 2009
San Diego, CA · 7 mi from La Mesa
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Simple Pest Management

Simple Pest Management

4.8 47 reviews
“! Both of them explained the process thoroughly and were clear about what they needed to do in order to clear my home of this vermin”
Responds within 10 min16,000+ homes servedSince 2019Serves San Diego County, Riverside County +4Free consultationLicensed
Santee, CA · 6 mi from La Mesa
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Listed for homeowners in and around La Mesa, CA, these 15 companies treat pest problems in homes. The pests each company names, its licensing claims and its hours come from its own site; ratings and the quoted comments come from public reviews.

Area overview: La Mesa, CA

The 15 companies on this page are rated from 4.6 to 5.0 across 2,113 reviews; 10 have 50 or more reviews. When customers rate these companies on specific qualities, they most often praise professionalism (90%), responsiveness (87%) and punctuality (82%). The topics that come up most in reviews of the companies on this page are "knowledge" and "price". 1 is open around the clock; 6 are open on Saturdays and 2 on Sundays. The services the companies on this page list most often on their websites are commercial pest control (2), residential pest control (2) and rodent control (2). 5 show a license on their websites and 8 have a BBB rating of A or A+. 11 have ten or more years of experience, the longest 75 years. 1 offers emergency call-outs; 1 offers financing or payment plans; 5 give free estimates; 4 are family- or locally-owned and 2 list coupons or special offers. 1 has Spanish-speaking staff. We have a website on file for all 15 of the companies on this page; all 15 publish a contact page; 10 list a public email and 1 takes bookings online. We count these figures across the companies on this page; distances are straight-line, and hours and prices change, so confirm the details with the company before you book.

Can I book a pest control visit on a Saturday?

Weekend hours are listed by 6 of the 15 companies here, which helps because you need to be home for an interior treatment. Ask how long you must stay out of treated rooms before you book the appointment for a Saturday morning.

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RED E Pest Prevention

RED E Pest Prevention

5.0 50 reviews
“Ethan let me know he was on his way to my home, arrived at the scheduled time, provided a written cost sheet and explained what he was going to do.”
InsuredServes Santee, Lakeside +2Family-ownedSince 2016
Santee, CA · 6 mi from La Mesa
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Queenb Live Bee Removal

Queenb Live Bee Removal

4.9 49 reviews
“Roman, of Queen B live bee removal service, did an excellent job removing a swarm of honey bees that had decided to nest on my roof.”
Free estimatesServes San Diego County, San Diego +17Family-ownedLicensedOpen 24 hoursSince 2018
San Diego, CA · 7 mi from La Mesa
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Suncoast Pest Management

Suncoast Pest Management

4.9 50 reviews
“From scheduling the appointment to addressing my inquiries, every interaction was met with courtesy, efficiency, and a genuine desire to ensure customer satisfaction.”
87% offFree consultationSatisfaction guaranteeServes La Jolla, CA, La Mesa, CA, San Diego, CALicensedSince 2018
Santee, CA · 6 mi from La Mesa
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American Pest Control

American Pest Control

4.6 43 reviews
“He's very pleasant and friendly and my experience with America Pest Control has always been positive !!”
Insured & bondedSince 1962Serves San Diego County, CAWomen-ownedBBB A+
Lemon Grove, CA · 2 mi from La Mesa
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Cal Coast Pest Management

Cal Coast Pest Management

5.0 29 reviews
“I appreciate that he comes in and asks if there is something specific he should look out for before he starts, Gives you a rundown of everything when he's done with the service.”
15% offFree estimates5,500+ clients servedBBB accreditedSince 2018Prices online
National City, CA · 9 mi from La Mesa
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Jamul Pest Control

Jamul Pest Control

4.9 47 reviews
“I heard them early morning that woke me up and called Jamul Pest control that same morning.”
Free estimatesLicensedSince 2016Serves San Diego County, CAFamily-ownedLocally owned
Spring Valley, CA · 4 mi from La Mesa
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Eliminite Termite

Eliminite Termite

4.9 20 reviews
“Explained the warranty, and made sure they answered all of our questions.”
10% offCalifornia license #PR6343NPMA memberSince 2011Serves San Diego, Ca, Orange County, Ca, Riverside, CaFamily-owned
Santee, CA · 6 mi from La Mesa
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Powell Termite & Pest Control

Powell Termite & Pest Control

4.8 10 reviews
“The entire fumigation process took just two days, and I was back home before I knew it.”
Free estimatesInsured25+ yearsServes San Diego County, Santee +5Licensed
Santee, CA · 6 mi from La Mesa
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W² Termite & Pest Management

W² Termite & Pest Management

4.9 12 reviews
“He and Chad did a thorough job of eliminating our home's subterranean termite problem, and I would would recommend him for anyone that needs good quality termite control service for a reasonable price.”
Free estimatesServes San DiegoBBB A+Since 2014
Santee, CA · 6 mi from La Mesa
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HomePest Control CompaniesCaliforniaLa Mesa, CA

Why these companies made our list

What customers say about companies near La Mesa

  • “A very professional and knowledgeable team. Highly recommended for termite inspection and extermination services!” — customer of Nixtermite Inc.
  • “The technicians were prompt and courteous, they explained the procedure and answered questions I asked.” — customer of Eliminite Termite
  • “John is our guy! He remembers everything, every time he comes and keeps such an attention to detail each and every time.” — customer of Jamul Pest Control
  • “On the day of fumigation, Joey kept me updated on the team’s arrival time and answered several questions that I had.” — customer of Cal Coast Pest Management

Excerpts from public reviews of the companies listed on this page.

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