Best Pest Control Services in Santee, CA

15 companies listed · 8 in Santee · 6 open weekends · all 15 rated 4.5+ · 4 show a license

Data verified October 18, 2026

Xtermite Inc

Xtermite Inc

4.6 48 reviews
“We have been Xtermite customers for a number of years now and have found them to be a reliable company with competent technicians that keep their promises with excellent performance!”
California license #3336Insured2-yr warrantySince 1998Serves San Diego County, Orange County, Riverside CountyBBB A+
10107 Prospect Ave B
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Simple Pest Management

Simple Pest Management

4.8 47 reviews
“Everything about this service from finding them on Yelp to setting the appointment to having the work done went smoothly.”
Responds within 10 min16,000+ homes servedSince 2019Serves San Diego County, Riverside County +4Free consultationLicensed
10739 Woodside Ave Ste A
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Book onlineBook
RED E Pest Prevention

RED E Pest Prevention

5.0 50 reviews
“Ethan, owner of RED E Pest, did a very thorough and detailed job at my house spraying for ants and cleaning webs.”
InsuredServes Santee, Lakeside +2Family-ownedSince 2016
10904 Eddington Rd
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Suncoast Pest Management

Suncoast Pest Management

4.9 50 reviews
“I always appreciate the cleanup of the spider webs under the eves and even the patio furniture.”
87% offFree consultationSatisfaction guaranteeServes La Jolla, CA, La Mesa, CA, San Diego, CALicensedSince 2018
10925 Hartley Rd Suite E
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Eliminite Termite

Eliminite Termite

4.9 20 reviews
“Communication was clear and professional, the workers came promptly and even called before arriving.”
10% offCalifornia license #PR6343NPMA memberSince 2011Serves San Diego, Ca, Orange County, Ca, Riverside, CaFamily-owned
10960 Wheatlands Ave #106
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Powell Termite & Pest Control

Powell Termite & Pest Control

4.8 10 reviews
“I have used he and his team to tent my house for termites as well, and have him to my house monthly for pests control.”
Free estimatesInsured25+ yearsServes San Diego County, Santee +5Licensed
10911 Wheatlands Ave
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Listed for homeowners in and around Santee, CA, these 15 companies treat pest problems in homes. The pests each company names, its licensing claims and its hours come from its own site; ratings and the quoted comments come from public reviews.

Area overview: Santee, CA

8 of the 15 companies we list are based in Santee; the other 7 serve Santee from San Diego (8 mi), Lemon Grove (8 mi) and Spring Valley (9 mi). The companies on this page are rated from 4.6 to 5.0 across 2,641 reviews; 11 have 50 or more reviews. When customers rate these companies on specific qualities, they most often praise professionalism (88%), responsiveness (87%) and punctuality (84%). 6 are open on Saturdays and 3 on Sundays. The services the companies on this page list most often on their websites are commercial pest control (3), rodent control (3), bed bug control (2), gopher control (2) and residential pest control (2). 4 show a license on their websites and 6 have a BBB rating of A or A+. 11 have ten or more years of experience, the longest 75 years. 1 offers financing or payment plans; 5 give free estimates; 4 are family- or locally-owned and 2 list coupons or special offers. We have a website on file for all 15 of the companies on this page; 14 publish a contact page; 11 list a public email and 1 takes bookings online. We count these figures across the companies on this page; distances are straight-line, and hours and prices change, so confirm the details with the company before you book.

Can I book a pest control visit on a Saturday?

Weekend hours are listed by 6 of the 15 companies here, which helps because you need to be home for an interior treatment. Ask how long you must stay out of treated rooms before you book the appointment for a Saturday morning.

W² Termite & Pest Management

W² Termite & Pest Management

4.9 12 reviews
“It was a great experience to see Andy & his extermination team work there knowledge & skilled hands safely on and around property as they put and end to our problems.”
Free estimatesServes San DiegoBBB A+Since 2014
9625 Mission Gorge Rd B2-344
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XT-2000 Inc.

XT-2000 Inc.

5.0 3 reviews
“It's highly effective in eliminating termites, environmentally friendly, and John's dedication to our satisfaction has been exceptional.”
Since 2003
10054 Prospect Ave # P
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Harbor Pest Control

Harbor Pest Control

4.7 46 reviews
“We've been using the same company for 20+ years because they are always prompt for inspections, seem very thorough with the inspections, and have very pleasant, personable personnel.”
Since 1948Serves Coronado, La Jolla +2Free consultationBBB accreditedFamily-ownedLocally owned
San Diego, CA · 8 mi from Santee
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Pest Patrol

Pest Patrol

4.9 48 reviews
“Not only are they so efficient and good at what they do, the team is AMAZING!”
Coupons & offersFree consultationSince 1982Family-owned
San Diego, CA · 8 mi from Santee
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Thrasher Pest Control

Thrasher Pest Control

4.9 50 reviews
“Mark is very knowledgeable about particular problems on our property, points out things I should be aware of, and gets the job done thoroughly and completely every time.”
Same-day response6,500+ clients servedServes San Diego CountyFamily-ownedLicensedSince 2009
San Diego, CA · 8 mi from Santee
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Attic Projects Company

Attic Projects Company

4.9 49 reviews
“Kevin came out, super friendly, on time, professional, looked at the project thoroughly, took pictures and measurements, ran calculations and gave us a very reasonable quote for work on our attic...”
Free estimatesLicensed15,000+ homeowners servedSince 2018Financing
San Diego, CA · 8 mi from Santee
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San Diego Bee Sanctuary

San Diego Bee Sanctuary

5.0 49 reviews
“These guys are great and they removed the Beehive safely and when I called of the urgency because of where was located they were very prompt and got out here right away.”
Licensed & insuredSince 2022
San Diego, CA · 8 mi from Santee
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American Pest Control

American Pest Control

4.6 43 reviews
“I also used them about 7 years ago for fumigation of a house for termites and also did a great job.”
Insured & bondedSince 1962Serves San Diego County, CAWomen-ownedBBB A+
Lemon Grove, CA · 8 mi from Santee
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Jamul Pest Control

Jamul Pest Control

4.9 47 reviews
“They came out to my house and finished the work in 20 mins.”
Free estimatesLicensedSince 2016Serves San Diego County, CAFamily-ownedLocally owned
Spring Valley, CA · 9 mi from Santee
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HomePest Control CompaniesCaliforniaSantee, CA

Why these companies made our list

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